When a group of animal-rights activists raid a testing facility in London, they inadvertently free a group of chimps infected with a contagion described by a terrified researcher simply as "rage." The chimps brutally attack the activists and the researcher, thus spreading the terrible virus into the general population.
28 days after the incident, a bicycle messenger named Jim (Murphy) awakens from a coma to find both the hospital and the city beyond completely deserted. He wanders through the uninhabited streets, finally taking shelter in a church, where he makes a gruesome discovery. Just as a red-eyed, murderous priest attacks, Jim is saved by a pair of armed survivors, who take him to safety.
The survivors, Selena (Harris) and Mark (Noah Huntley), explain to Jim that the infection first manifested as riots and soon spread through entire population of London, possibly further. The virus is transmitted in blood and saliva and takes effect within seconds. There is no known cure. Despite the danger, Jim insists on returning home, where he discovers that his parents are not among the survivors.
Later, Jim and Selena meet up with a father (Gleeson) and daughter (Burns) who convince them to follow a radio message calling for survivors to head to a blockade in the north. The four set out together in search of what the broadcast claims to be the "answer to infection." They discover the source of the signal in Manchester, where a military unit has established a self-sustained existence within a large estate. Little do they know, however, their troubles are far from over.
It isn't over 'til it's over





